Sheldon C. Reed, Ph.D. (November 7, 1910–February 1, 2003): Genetic Counseling, Behavioral Genetics

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Frontotemporal dementia: genetics and genetic counseling dilemmas.

BACKGROUND Frontotemporal dementia (FTD) is a neurodegenerative disease with early symptoms of personality change and/or language disorder. Approximately 40% of individuals with FTD have a family history of dementia; however, in our experience, less than 10% have clear autosomal dominant inheritance. Mutations in the microtubule-associated protein tau (MAPT) gene have been reported in up to 50%...

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CHAPTER 1 Behavioral Genetics

Behavioral genetics is a science with dual origins and goals. The study of behavioral genetics that originated in psychology is primarily concerned with the causes of individual variation. The Behavior Genetics Association and its journal, Behavior Genetics, have this as their focus. The emphasis is mainly on the genetics of human behavior and mind. Nonhuman animal, mainly rodent, studies of ge...

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Science Selections November 2003

Propylthiouracil (PTU) and methimazole (MMI) are the most commonly used antithyroid drugs. The available data suggest that these drugs may block the thyroid hormone synthesis by inhibiting the thyroid peroxidase (TPO) or diverting oxidized iodides away from thyroglobulin. It is also known that PTU inhibits the selenocysteine-containing enzyme ID-1 by reacting with the selenenyl iodide intermedi...

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Corrections November 2003

an Appropriate Basis for Nuclear Worker Compensation? Wakeford (2003) and Little (2003) wrote in response to our comments about the use of A-bomb survivor studies as a basis for U.S. nuclear worker compensation decisions (Wing and Richardson 2002). Wakeford (2003) disagrees with our statement (Wing and Richardson 2002) that there is discrepancy between childhood cancer risk estimates from in ut...

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ژورنال

عنوان ژورنال: The American Journal of Human Genetics

سال: 2003

ISSN: 0002-9297

DOI: 10.1086/376611